Speed up counting,
maintain accuracy
Corning Cell Counter
Counting cells is a routine task for any researcher working with cell cultures. Obtaining accurate cell counts is important for both cell expansion as well as cell seeding for experiments. Automated cell counting can speed up your workflow and eliminate user-to-user differences.
The name Corning Cell Counter comes from our agreement with Corning on the distribution of our product. We have come to an agreement for the exclusive distribution of our cell counting technology, hence the name Corning Cell Counter.
Small footprint, reduces waste and looks good too!
"High quality results and easy to use. I particularly like the fact that reusable glass hemocytometers are used, reducing waste and running costs."
Great device, saves a lot of time
"Easy to use, high quality and reproducible cell counting. Customer support is very professional."
Highly recommended
"Everyone in the lab is pretty enthusiastic about the cell counter compared to the alternative or formerly applied methods/devices for a number of reasons: tiny dimensions of the device, easily installed, intuitive use (check the YouTube video!), improved data quality, less time consuming working step. For a quick estimation of the cell number: suspension cells can even be directly measured in the culture flask without loading onto the counting chamber."
Great staple for cell culture!
"The Corning Cell Counter has become a staple in my cell culture lab. It's easy and fast assessment of cell density is something that I rely on every day. It is a product that gives reliable results, and I love that I can see both the raw images and the analyzed images easily."
A time saver
"Absolutely. Very easy to use, and yields reproducible results. We are able to quickly perform cell counts on dozens of samples in rapid succession - whereas the traditional methods for trypan blue counting were much more labor intensive."
Counting is fast and reliable. I would definitely buy it again.
"We compared the cell counter with manually counting. The data matches very nicely if you do not overload the slides with too high a cell density. To get reliable data, high debris content should also not be present."
Real-time gating
Adapt size gating to your cells
The Corning Cell Counter generates images that are automatically analyzed using our state-of-the-art cell counting algorithm. Images are processed within seconds and can be used to count both mammalian cells and organoids. This allows you to quickly obtain an accurate overview of the cell concentration of your sample. Users can optimize their cell counts by gating the size range to the cell type that is being analyzed. The gates and corresponding concentration, cell size, and viability analysis can be adapted in real-time.
Analyze cell size and number
All your sample data in one place
Images and numerical data of the cell counts are collected into an online report. The report provides an overview of the cell concentration, size and, if desired, cell viability. Reports and raw images can be stored online in the CytoSMART Cloud and are always available for download.
Identify single cells in clusters
The analysis is effective in single cell recognition, even for clumpy cells
Identifying single cells using image analysis is relatively straightforward. Cell recognition can be achieved using small parameter sets that contain features like cell size, edge thickness, and circularity. However, some cell types tend to be sticky and form clumps, making it challenging to count individual cells within the formed clusters. The image analysis algorithms of the Corning Cell Counter are supported by machine learning, where the parameter set has been extended to 350,000 and is optimized to clearly distinguish cell boundaries, even in samples that are highly crowded.
Want to see if the Corning Cell Counter is a good fit for your Lab?
Organoid Counting
Perform organoid counts on your own transparent counting slide
The popularity of organoid culturing has significantly spiked in the past decade. Organoids are 3D cell structures that contain a multitude of organ-specific cells. While these structures have a high potential in many life science research fields, they are laborious to develop and maintain. The Corning Cell Counter can be equipped with the CytoSMART organoid counting algorithm that can be used to standardize and speed up a routine part of the organoid culturing process.
Determine sample variance
Improve your data accuracy by increasing the counting area
The multi-count function of the Corning Cell Counter allows users to take up to 8 counts of the same sample. When multiple counts are taken at various locations within the hemocytometer, the variability between counts can be investigated. The software allows for easy numerical and visual comparison between selected counts, including the calculation of averages and standard deviation.
Use the counting chamber that you already own
Compatible with hemocytometers and other transparent counting chambers
The Corning Cell Counter is developed to be used in combination with reusable (glass) or disposable (plastic) cell counting slides, with or without a counting grid, including the CytoSMART disposable/reusable cell counting slides. The only requirement is the depth of the cell counting chamber, which needs to be 0.1 mm for counting mammalian cells and 0.2 mm for organoids.
Technical specifications
| Counting range (concentration/mL) | (5.0 × 10^4) – (1.0 × 10^7) |
|---|---|
| Size range - mammalian cells | 4 – 70 µm |
| Size range - organoids | 10 – 100 µm/200 µm* |
| Measurement time** | <3 sec |
| Weight | 1 kg |
| Field of view | 1.5 mm × 1.5 mm |
| Magnification | 10× (0.96 µm/pixels) |
| Autofocus | Yes |
| Image resolution | 1536 × 1536 pixels |
| Data formats | JPG, CSV, PDF |
| Light source | LED |
| Camera | 5.0 MP CMOS |
| Dimensions (L × W × H) | 122 mm × 122 mm × 125 mm |
| Operating environment | 5 – 40 °C, 20 – 95% humidity |
| * size limit depends on the dimensions of the counting chamber | |
| ** at 73 Mbps download and 20 Mbps upload speed | |
| Research use only. Not intended for diagnostic purposes |
Videos
Downloads
Example count report Corning Cell Counter
example-count-report-Corning-Cell-Counter ( PDF - 4 MB )
Automated organoid counting - brochure
automated-organoid-counting-brochure-cytosmart ( PDF - 2 MB )
CCC case study Beyond Cell Counting To Study Leukemia
CCC-case-study-Beyond-Cell-Counting-To-Study-Leukemia ( PDF - 147 KB )
Cell Lines Corning Cell Counter
Cell-Lines-Corning-Cell-Counter ( PDF - 77 KB )
Frequently Asked Questions
When using Trypan Blue, the device can determine cell viability as well.
The device is easy to clean using lint-free wipes and ethanol (70%) or isopropyl alcohol (IPA). Do not use acetone to clean the device, also the device cannot be autoclaved.
The Corning Cell Counter is compatible with reusable (glass) and disposable (plastic) counting chambers.
No calibration of the device is required.
The device requires a dedicated desktop or laptop running on Windows 10 or above, with a USB3 port and an active internet connection. A WiFi or Ethernet connection is necessary for connecting to the CytoSMART Cloud for image analysis and storage.
Publications
Potentiation of electrochemotherapy effectiveness by immunostimulation with IL-12 gene electrotransfer in mice is dependent on tumor immune status
A novel ultra‐low conductivity electromanipulation buffer improves cell viability and enhances dielectrophoretic consistency
Dicamba elevates concentrations of S-adenosyl methionine but does not induce oxidative stress or alter DNA methylation in rainbow trout (Oncorhynchus mykiss) hepatocytes