Corning Cell Counter

Speed up counting,
maintain accuracy

  • Corning Cell Counter

Corning Cell Counter

Counting cells is a routine task for any researcher working with cell cultures. Obtaining accurate cell counts is important for both cell expansion as well as cell seeding for experiments. Automated cell counting can speed-up your workflow and eliminate user-to-user differences.

The name Corning Cell Counter comes from our agreement with Corning on the distribution of our product. We have come to an agreement for the exclusive distribution of our cell counting technology, hence the name Corning Cell Counter.

Small footprint, reduces waste and looks good too!

Gillian Kay Hebrew University

"High quality results and easy to use. I particularly like the fact that reusable glass hemocytometers are used, reducing waste and running costs."

4.7
Application Area: Cell Counting

Great device, saves a lot of time

Rinaldo van Meel Zuyd University

"Easy to use, high quality and reproducible cell counting. Customer support is very professional."

5.0

Highly recommended

Karl Kramer Technical University Of Munich

"Everyone in the lab is pretty enthusiastic about the cell counter compared to the alternative or formerly applied methods/devices for a number of reasons: tiny dimensions of the device, easily installed, intuitive use (check the YouTube video!), improved data quality, less time consuming working step. For a quick estimation of the cell number: suspension cells can even be directly measured in the culture flask without loading onto the counting chamber."

4.3

Great staple for cell culture!

Caroline Easton Sapidyne Instruments

"The Corning Cell Counter has become a staple in my cell culture lab. It's easy and fast assessment of cell density is something that I rely on every day. It is a product that gives reliable results, and I love that I can see both the raw images and the analyzed images easily."

5.0

A time saver

David Wallace Oklahoma State University Center for Health Sciences

"Absolutely. Very easy to use, and yields reproducible results. We are able to quickly perform cell counts on dozens of samples in rapid succession - whereas the traditional methods for trypan blue counting were much more labor intensive."

5.0

Counting is fast and reliable. I would definitely buy it again.

Iris Augustin Hochschule Weihenstephan-Triesdorf

"We compared the cell counter with manually counting. The data matches very nicely if you do not overload the slides with too high a cell density. To get reliable data, high debris content should also not be present."

4.7
Application Area: Cell biology

Real time gating

Adapt size gating to your cells

The Corning Cell Counter generates images that are automatically analyzed using our state-of-the-art cell counting algorithm. Images are analyzed within seconds and can be used to count both mammalian cells and organoids. This allows you to quickly obtain an accurate overview of the cell concentration of your sample. Users can optimize their cell counts by gating the size range to the cell type that is being used. The gates and corresponding concentration, cell size and viability analysis can be adapted in real time.

Obtain cell population number and size

All your sample data in one place.

Images and numerical data of the cell counts are collected into an online report. The report provides an overview of the cell concentration, size and, if desired, cell viability. Reports and raw images can be stored online in the CytoSMART Cloud environment and are always available for download.

Identify single cells in clusters

The analysis is effective in single cell recognition, even for sticky cells

To identify single cells using image analysis is relatively straightforward. Cell recognition can be achieved using small parameter sets that contain features like cell size, edge thickness and circularity. Some cell types however are known to stick together and as a consequence would be difficult to single out. The image analysis algorithms in the Corning Cell Counter are supported by machine learning where the parameter set has been extended to three-hundred and fifty thousand and is optimized to clearly distinguish cell boundaries, even in samples that are highly crowded.

Want to see if the Corning Cell Counter is a good fit for your Lab?

Organoid Counting - New Feature

Perform organoid counts on your own transparent counting slide

The popularity of organoid culturing has spiked in the past decade since the publication of Sato et al. 2009, in which the development of intestinal crypt-villus structures is postulated. The three-dimensional niche-like structures within organoids are highly similar to in situ physiology. While these structures have a high potential in many life-science research fields, they are laborious to develop and maintain. The Corning Cell Counter can be equipped with an algorithm for organoid counting that can be used to standardize and speed-up a routine part of organoid culturing.

Determine sample variance

Improve your data accuracy by increasing the counting area

The multi-count function of the Corning Cell Counter allows users to take up to 8 counts of the same sample. When multiple counts are taken at various locations within the hemocytometer, the variability between counts can be investigated. The software allows for easy numerical and visual comparison between selected counts, including the calculation of averages and standard deviation.

Use the counting chamber that you already own

Compatible with hemocytometers and other transparent counting chambers

The Corning Cell Counter is developed to be used in combination with hemocytometers or any other transparent (disposable) counting slide, with or without a counting grid. Use reusable glass hemocytometers when you would like to reduce both operational costs and the environmental footprint of your lab. The only requirement of the counting slide is the depth, which needs to be 0.1 mm for mammalian cells and can be 0.2 mm for organoids.

Technical specifications

Counting range (concentration/mL) 5*10^4 – 1*10^7
Size range mammalian cells 4 ~ 70 µm
Size range organoids 10 - 100 µm or 10 - 200 µm (size limit depends on the dimensions of the counting chamber)
Measurement time (at 73 Mbps download and 20 Mbps upload speed) <3 sec
Weight 1 kg
Field of view 1.5 x 1.5 mm
Magnification 100X - 0.96 µm/pixels
Image resolution 1536 x 1536
Exported formats images and count reports JPG, CSV, PDF
Light source LED
Camera 5 MP CMOS
Unit dimensions 122 x 122 x 125 mm (LxWxH)
Operating environment 5-40 °C, 20-95% humidity
Research use only. Not intended for diagnostic purposes

Videos

Appnotes

Corning Cell Counter Automated Organoid Counting Appnote

Count organoids with the Corning Cell Counter
Download Appnote

Frequently Asked Questions

When using Trypan Blue, the device can determine viability as well.

The device is easy to clean using lint-free swipes and EtOH (70%) or IPA. Do not use Acetone to clean the device, also the device cannot be autoclaved.

No, the Corning Cell Counter also allows you to count using disposable counting slides.

No calibration by the user is needed for the device to operate.

The device can be used with a windows 10 laptop. A WiFi or Ethernet internet connection is recommended to be able to connect to the CytoSMART Cloud for data storage and analysis.