Cell Counter hero image 2020 4 10

Speed up counting,
maintain accuracy

Corning Cell Counter

Counting cells is a routine task for any researcher working with cell cultures. Obtaining accurate cell counts is important for both cell expansion as well as cell seeding for experiments. Automated cell counting can speed up your workflow and eliminate user-to-user differences.

The name Corning Cell Counter comes from our agreement with Corning on the distribution of our product. We have come to an agreement for the exclusive distribution of our cell counting technology, hence the name Corning Cell Counter.

scientists choice award badge

Small footprint, reduces waste and looks good too!

Gillian Kay Hebrew University

"High quality results and easy to use. I particularly like the fact that reusable glass hemocytometers are used, reducing waste and running costs."

4.7
Application Area: Cell Counting

Great device, saves a lot of time

Rinaldo van Meel Zuyd University

"Easy to use, high quality and reproducible cell counting. Customer support is very professional."

5.0

Highly recommended

Karl Kramer Technical University Of Munich

"Everyone in the lab is pretty enthusiastic about the cell counter compared to the alternative or formerly applied methods/devices for a number of reasons: tiny dimensions of the device, easily installed, intuitive use (check the YouTube video!), improved data quality, less time consuming working step. For a quick estimation of the cell number: suspension cells can even be directly measured in the culture flask without loading onto the counting chamber."

4.3

Great staple for cell culture!

Caroline Easton Sapidyne Instruments

"The Corning Cell Counter has become a staple in my cell culture lab. It's easy and fast assessment of cell density is something that I rely on every day. It is a product that gives reliable results, and I love that I can see both the raw images and the analyzed images easily."

5.0

A time saver

David Wallace Oklahoma State University Center for Health Sciences

"Absolutely. Very easy to use, and yields reproducible results. We are able to quickly perform cell counts on dozens of samples in rapid succession - whereas the traditional methods for trypan blue counting were much more labor intensive."

5.0

Counting is fast and reliable. I would definitely buy it again.

Iris Augustin Hochschule Weihenstephan-Triesdorf

"We compared the cell counter with manually counting. The data matches very nicely if you do not overload the slides with too high a cell density. To get reliable data, high debris content should also not be present."

4.7
Application Area: Cell biology

Real-time gating

Adapt size gating to your cells

The Corning Cell Counter generates images that are automatically analyzed using our state-of-the-art cell counting algorithm. Images are processed within seconds and can be used to count both mammalian cells and organoids. This allows you to quickly obtain an accurate overview of the cell concentration of your sample. Users can optimize their cell counts by gating the size range to the cell type that is being analyzed. The gates and corresponding concentration, cell size, and viability analysis can be adapted in real-time.

Analyze cell size and number

All your sample data in one place

Corning cell counter cell size historgram

Images and numerical data of the cell counts are collected into an online report. The report provides an overview of the cell concentration, size and, if desired, cell viability. Reports and raw images can be stored online in the CytoSMART Cloud and are always available for download.

Identify single cells in clusters

The analysis is effective in single cell recognition, even for clumpy cells

All images cluster separation algorithm small v2

Identifying single cells using image analysis is relatively straightforward. Cell recognition can be achieved using small parameter sets that contain features like cell size, edge thickness, and circularity. However, some cell types tend to be sticky and form clumps, making it challenging to count individual cells within the formed clusters. The image analysis algorithms of the Corning Cell Counter are supported by machine learning, where the parameter set has been extended to 350,000 and is optimized to clearly distinguish cell boundaries, even in samples that are highly crowded.

Want to see if the Corning Cell Counter is a good fit for your Lab?

Organoid Counting

Perform organoid counts on your own transparent counting slide

Organoid counting v1

The popularity of organoid culturing has significantly spiked in the past decade. Organoids are 3D cell structures that contain a multitude of organ-specific cells. While these structures have a high potential in many life science research fields, they are laborious to develop and maintain. The Corning Cell Counter can be equipped with the CytoSMART organoid counting algorithm that can be used to standardize and speed up a routine part of the organoid culturing process.

Determine sample variance

Improve your data accuracy by increasing the counting area

The multi-count function of the Corning Cell Counter allows users to take up to 8 counts of the same sample. When multiple counts are taken at various locations within the hemocytometer, the variability between counts can be investigated. The software allows for easy numerical and visual comparison between selected counts, including the calculation of averages and standard deviation.

Use the counting chamber that you already own

Compatible with hemocytometers and other transparent counting chambers

Cell Counter top view web 2020 4 10

The Corning Cell Counter is developed to be used in combination with reusable (glass) or disposable (plastic) cell counting slides, with or without a counting grid, including the CytoSMART disposable/reusable cell counting slides. The only requirement is the depth of the cell counting chamber, which needs to be 0.1 mm for counting mammalian cells and 0.2 mm for organoids.

Technical specifications

Counting range (concentration/mL)(5.0 × 10^4) – (1.0 × 10^7)
Size range - mammalian cells4 – 70 µm
Size range - organoids10 – 100 µm/200 µm*
Measurement time**<3 sec
Weight1 kg
Field of view1.5 mm × 1.5 mm
Magnification10× (0.96 µm/pixels)
AutofocusYes
Image resolution1536 × 1536 pixels
Data formatsJPG, CSV, PDF
Light sourceLED
Camera5.0 MP CMOS
Dimensions (L × W × H)122 mm × 122 mm × 125 mm
Operating environment5 – 40 °C, 20 – 95% humidity
* size limit depends on the dimensions of the counting chamber
** at 73 Mbps download and 20 Mbps upload speed
Research use only. Not intended for diagnostic purposes

Videos

Frequently Asked Questions

When using Trypan Blue, the device can determine cell viability as well.

The device is easy to clean using lint-free wipes and ethanol (70%) or isopropyl alcohol (IPA). Do not use acetone to clean the device, also the device cannot be autoclaved.

The Corning Cell Counter is compatible with reusable (glass) and disposable (plastic) counting chambers.

No calibration of the device is required.

The device requires a dedicated desktop or laptop running on Windows 10 or above, with a USB3 port and an active internet connection. A WiFi or Ethernet connection is necessary for connecting to the CytoSMART Cloud for image analysis and storage.

Publications

Sign up now

Want to stay up to date? Sign up for our newsletter

No, thanks